HISTIOCITOSIS DE CELULAS DE LANGERHANS PULMONAR PDF

Blood 22 : , J Exp Med 4 : , N Engl J Med 9 : , N Engl J Med 3 : , Lancet : , Hematol Oncol Clin North Am 29 5 : ,

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TABLA 1. These entities make up a heterogeneous group, and are mainly classified as Langerhans cell histiocytoses and non-Langerhans cell histiocytoses. Langerhans cell histiocytoses have as a common characteristic the proliferation of dendritic antigen-presenting cells with phenotypical and ultrastructural characteristics of Langerhans cells.

Infiltration may be limited to one organ, or may be disseminated. The prognosis and the treatment especially depend on the age of the patient and the number and dysfunction of the organs involved.

Its etiopathogenesis is unknown, although most researchers currently believe that an alteration in the regulation of the immunological system occurs in these patients. Sin embargo, existen proliferaciones clonales que son benignas. Posteriormente otros autores no han conseguido demostrar estos hallazgos Lesiones en ingles. Lesiones anogenitales. El compromiso de las mucosas es excepcional.

Hematoxilina-eosina, x CD1a, x En las formas nodulares puede invadir la hipodermis. En las primeras, el signo de Darier es positivo. La rapidez de respuesta al tratamiento.

A veces es necesaria la radioterapia. En casos refractarios existen otras alternativas como ciclosporina, metotrexato o talidomida 8,64,

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